abstract：BACKGROUND:Pterygium is a condition characterized by epithelial overgrowth of the cornea, inflammatory cell infiltration and an abnormal extracellular matrix accumulation. Chronic UV exposure is considered as a pathogenic factor of this disease. Proteasome is an intracellular multi-subunit protease complex that degrade...

journal_title：BMC ophthalmology

authors： Aletras AJ,Trilivas I,Christopoulou ME,Drakouli S,Georgakopoulos CD,Pharmakakis N

更新日期：2018-12-18 00:00:00

abstract：BACKGROUND:This study aimed to investigate patient adherence to face-down positioning (FDP) and non-supine positioning (NSP) following vitrectomy with gas tamponade for treating macular holes (MHs). METHODS:Nursing records of 92 patients who underwent vitrectomy with gas tamponade for small-diameter (diameter < 400 μm...

journal_title：BMC ophthalmology

authors： Morimoto E,Shimada Y,Sugimoto M,Mizuguchi T,Tanikawa A,Horiguchi M

更新日期：2018-12-14 00:00:00

abstract：BACKGROUND:To describe the superiority of ocular ultrasound in the diagnostic management of extrascleral extension in choroidal melanoma. CASE PRESENTATION:We present a case of a 94-year-old male with choroidal melanoma of the right eye imaged with MRI and ocular ultrasound to aid in the detection of extrascleral exte...

journal_title：BMC ophthalmology

authors： Jacobsen BH,Ricks C,Harrie RP

更新日期：2018-12-12 00:00:00

abstract：BACKGROUND:To report a case of multiple evanescent white dot syndrome (MEWDS) following simultaneous rabies vaccination. CASE PRESENTATION:Review of the clinical, laboratory, photographic, optical coherence tomographic (OCT), fundus autofluorescent, angiographic, electrophysiologic, and perimetric records of a patient...

journal_title：BMC ophthalmology

authors： Yang JS,Chen CL,Hu YZ,Zeng R

更新日期：2018-12-07 00:00:00

abstract：BACKGROUND:Previous techniques resulted with low rates of successful fusion after the surgeries and high necessity of additional surgeries in the treatment of thyroid orbitopathy related strabismus. In this study, reviewing the results of our patients who had surgical correction with relaxed muscle positioning techniqu...

journal_title：BMC ophthalmology

authors： Sarici AM,Mergen B,Oguz V,Dogan C

更新日期：2018-11-23 00:00:00

abstract：BACKGROUND:To investigate the effect of idiopathic epiretinal membrane (ERM) on the retinal-image quality and psychophysical contrast sensitivity function (CSF). METHODS:Forty-four subjects with diagnosis of idiopathic unilateral ERM were enrolled in this cross-sectional observational clinical study. The fellow unaffe...

journal_title：BMC ophthalmology

authors： Liu L,Wang Y,Liu J,Liu W

更新日期：2018-11-07 00:00:00

abstract：BACKGROUND:Polypoidal choroidal vasculopathy (PCV) consists of polyps that potentially cause massive subretinal hemorrhage and their branching vascular network (BVN) of feeder vessels. Although conventional indocyanine green angiography (IA) has shown anti-vascular endothelial growth factor (VEGF) agents and/or photody...

journal_title：BMC ophthalmology

authors： Iesato Y,Tanaka M,Murata M,Kitahara J,Hirano T,Kurenuma T,Yoshida N,Murata T

更新日期：2018-11-03 00:00:00

abstract：BACKGROUND:To study the healing processes of partial thickness wounds in the adult rabbit cornea after grafting a porous collagen-glycosaminoglycan copolymer matrix (CG). METHODS:In this study, the regeneration of surgically-induced rabbit corneal defect implanted with CG was investigated. The corneal partial thicknes...

journal_title：BMC ophthalmology

authors： Wu SY,Pan CY,Shen EP,Tzeng IS,Hsu WC

更新日期：2018-10-25 00:00:00

abstract：BACKGROUND:To report a patient who presented with bluish scleral discoloration, keratoconus, and progressive high myopia. CASE PRESENTATION:A 6-year-old Chinese female patient presented with a significant bluish discoloration of the sclera in both eyes and extreme corneal thinning with anterior corneal protrusion. Gen...

journal_title：BMC ophthalmology

authors： Wan Q,Tang J,Han Y,Xiao Q,Deng Y

更新日期：2018-09-18 00:00:00

abstract：BACKGROUND:The purpose of this study was to identify the genetic cause and describe the clinical phenotype of Schnyder corneal dystrophy (SCD) in six unrelated probands. METHODS:We identified two white Czech, two white British and two South Asian families with a clinical diagnosis of SCD. Ophthalmic assessment include...

journal_title：BMC ophthalmology

authors： Evans CJ,Dudakova L,Skalicka P,Mahelkova G,Horinek A,Hardcastle AJ,Tuft SJ,Liskova P

更新日期：2018-09-17 00:00:00

abstract：BACKGROUND:Bone marrow transplantation retinopathy is a rare condition affecting the posterior pole. The purpose of this case report is to highlight the possible risk factors and clinical features. CASE PRESENTATION:A 19y old male with relapsed and refractory acute lymphoblastic leukaemia was admitted under haematolog...

journal_title：BMC ophthalmology

authors： Butt F,McKibbin M

更新日期：2018-09-14 00:00:00

abstract：BACKGROUND:Endogenous endophthalmitis could lead to a devastating outcome without a prompt and appropriate management. We report a case of advanced endogenous Klebsiella pneumoniae endophthalmitis with extensive subretinal abscess that was successfully treated with a vitrectomy. CASE PRESENTATION:A systemically well 6...

journal_title：BMC ophthalmology

authors： Xu H,Fu B,Lu C,Xu L,Sun J

更新日期：2018-09-05 00:00:00

abstract：BACKGROUND:Nocardia infection is uncommon in clinical practice, with most cases occuring as the result of opportunistic infection in immunocompromsed patients. Here, we report a case of disseminated nocardiosis with subretinal abscess in a patient with nephrotic syndrome, and whom is receiving immunosuppressive therapy...

journal_title：BMC ophthalmology

authors： Xu H,Fu B,Xu L,Sun J

更新日期：2018-09-03 00:00:00

abstract：BACKGROUND:Idiopathic elevated episcleral venous pressure (IEEVP) or idiopathic dilated episcleral veins (IDEV) is a rare abnormality, and thus therapeutic treatment for this condition rarely is discussed. We report a case of a patient with bilateral glaucoma secondary to IDEV for whom intraocular pressures (IOPs) were...

journal_title：BMC ophthalmology

authors： Rong X,Li M

更新日期：2018-08-23 00:00:00

abstract：BACKGROUND:To investigate the ability of characterizing neonatal retinal hemorrhage (RH) using RetCam in healthy newborns and the systemic effects during the procedure. METHODS:This prospective study enrolled 68 healthy newborns aged 2 to 4 days old. The RH was imaged and classified according to the location and numbe...

journal_title：BMC ophthalmology

authors： Chen F,Cheng D,Pan J,Huang C,Cai X,Tian Z,Lu F,Shen L

更新日期：2018-08-20 00:00:00

abstract：BACKGROUND:Numerous studies have suggested that the integrity of the cone interdigitation zone (IZ) could be considered to be a marker of photoreceptor damage and its recovery. However, little is known about the IZ in healthy eyes. Our present study was to measure the cone IZ area by optical coherence tomography (OCT),...

journal_title：BMC ophthalmology

authors： Gu R,Deng G,Jiang Y,Jiang C,Xu G

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Orbital exenteration is a disfiguring procedure that aims to achieve local control. It is commonly a part of the management of malignant orbital tumor which is a life-threatening condition. It is necessary to determine predictive factors associated with overall survival (OS) following orbital exenteration. ...

journal_title：BMC ophthalmology

authors： Aryasit O,Preechawai P,Hirunpat C,Horatanaruang O,Singha P

更新日期：2018-07-28 00:00:00

abstract：BACKGROUND:To evaluate inner retinal dimples after peeling of the inner limiting membrane (ILM) for macular holes (lamellar macular hole [LMH] and full-thickness macular hole [FTMH]) via multiple imaging modes of spectral-domain optical coherence tomography (OCT) and to assess their relationship with preoperative vitre...

journal_title：BMC ophthalmology

authors： Liu J,Chen Y,Wang S,Zhang X,Zhao P

更新日期：2018-06-27 00:00:00

abstract：BACKGROUND:This study sought to identify factors associated with retinal detachment and retreatment of aggressive posterior retinopathy of prematurity (APROP) initially treated with intravitreal ranibizumab (IVR) injection as well as the efficacy of IVR treatment. METHODS:This was a retrospective study. A total of 83 ...

journal_title：BMC ophthalmology

authors： Tong Q,Yin H,Zhao M,Li X,Yu W

更新日期：2018-06-26 00:00:00

abstract：BACKGROUND:To report a case series in which a modified technique was used to remove retained submacular perfluorocarbon liquid (PFCL) secondary to vitreoretinal surgery for rhegmatogenous retinal detachment. CASE PRESENTATION:Four patients who had undergone pars plana vitrectomy for rhegmatogenous retinal detachment w...

journal_title：BMC ophthalmology

authors： Lin Z,Chen Y,Gao S,Zhong Y,Shen X

更新日期：2018-06-04 00:00:00

abstract：BACKGROUND:To analyze the positions of intraocular posterior Implantable Collamer Lens (ICL) and its possible relationship with vault. METHODS:This cross-sectional study included 72 patients with high myopia (134 eyes) who were followed up after phakic intraocular lens implantation. The postoperative time ranged from ...

journal_title：BMC ophthalmology

authors： Zhang X,Chen X,Wang X,Yuan F,Zhou X

更新日期：2018-05-09 00:00:00

abstract：BACKGROUND:Investigating the efficacy and safety of phacoemulsification with intraocular lens (IOL) implantation in corneal opacities. METHODS:This retrospective study was conducted in a tertiary medical center. Twenty-three eyes of 19 patients with cataracts and corneal opacities obscuring the pupillary center having...

journal_title：BMC ophthalmology

authors： Ho YJ,Sun CC,Chen HC

更新日期：2018-04-23 00:00:00

abstract：BACKGROUND:Perfluorocarbon liquid (PFCL) is widely used as an intraoperative heavy tamponade to flatten the retina and is replaced with silicone oil (SO) at the end of the surgery. Due to the long tamponade period, the SO is known to remain attached to the retina at the time of removal, and is commonly termed "sticky o...

journal_title：BMC ophthalmology

authors： Fukumoto M,Nishida Y,Kida T,Sato T,Kobayashi T,Ikeda T

更新日期：2018-03-27 00:00:00

abstract：BACKGROUND:To evaluate the changes of choroidal vascular structures in patients after phacoemulsification surgery. METHODS:A self-control study was conducted on 36 eyes of 36 patients who had uneventful phacoemulsification. Choroidal images were acquired preoperatively, 7 days (D7), 1 month (M1), and 3 months (M3) aft...

journal_title：BMC ophthalmology

authors： Chen H,Wu Z,Chen Y,He M,Wang J

更新日期：2018-03-23 00:00:00

abstract：BACKGROUND:Acute Posterior Multifocal Placoid Pigment Epitheliopathy (APMPPE) is a rare inflammatory eye disease that affects the Retinal Pigment Epithelium and outer retina. The purpose of this study was to describe its presentations, as well as its prognosis in a series of untreated patients. METHODS:Records of pati...

journal_title：BMC ophthalmology

authors： Xerri O,Salah S,Monnet D,Brézin AP

更新日期：2018-03-20 00:00:00

abstract：BACKGROUND:To evaluate the structural changes associated with visual acuity (VA) in patients with idiopathic macular telangiectasia (MT) type 1 using multimodal imaging modalities. METHODS:A retrospective study of 14 patients with MT type 1 and of 10 eyes from 10 healthy individuals as age-matched controls was conduct...

journal_title：BMC ophthalmology

authors： Guo J,Tang W,Ye X,Wu H,Xu G,Liu W,Zhang Y

更新日期：2018-03-05 00:00:00

abstract：BACKGROUND:While pars plana vitrectomy (PPV) has become the third most commonly performed surgery in the world, it can also induce multiple post complications easily. Among them, cataract progression is the most frequent one that can lead to blindness eventually. METHODS:To understand the underlying mechanisms of post...

journal_title：BMC ophthalmology

authors： Ji Y,Rong X,Lu Y

更新日期：2018-02-27 00:00:00

abstract：BACKGROUND:P66Shc is partially localised within the mitochondrial fraction. It is primarily related to the generation of mitochondrial reactive oxygen species and apoptosis. Based on previous studies, we hypothesize that in the retina, p66Shc may exist and affect the development of diabetic retinopathy. The purpose of ...

journal_title：BMC ophthalmology

authors： Zhao MH,Hu J,Li S,Wu Q,Lu P

更新日期：2018-02-27 00:00:00

abstract：BACKGROUND:Graves' disease is a common autoimmune inflammatory condition of the thyroid. About one in four of affected patients also develop orbital symptoms like exophthalmos, proptosis and diplopia - called Graves' Ophthalmopathy. Not all patients respond well to the standard therapy of systemic glucocorticoid admini...

journal_title：BMC ophthalmology

authors： Rau A,Klopfer M,Rommel N,Rau-Fornefeld M,Kolk A

更新日期：2018-02-27 00:00:00

abstract：BACKGROUND:To evaluate therapeutic outcomes of interferon alpha-2a (IFNα2a) treatment in patients with Behcet's disease who were refractory to immunosuppressive agents. METHODS:This retrospective case series reviewed the medical records of 5 patients with refractory Behcet uveitis from January 2011 to February 2017. I...

journal_title：BMC ophthalmology

authors： Lee JH,Lee CS,Lee SC

更新日期：2018-02-20 00:00:00

abstract：BACKGROUND:Adolescent KC is a special segment of the general KC population because an adolescents's eyes are still susceptible to blurred vision and optical defocus during the sensitive period of ocular and visual development. In the present study, we evaluated the ocular dimensions of 53 KC adolescents. METHODS:One h...

journal_title：BMC ophthalmology

authors： Jian W,Shen Y,Chen Y,Tian M,Zhou X

更新日期：2018-02-13 00:00:00

abstract：BACKGROUND:Older drivers aged ≥70 years old have among the highest rates of motor vehicle collisions (MVC) compared to other age groups. Driving is a highly visual task, and older adults have a high prevalence of vision impairment compared to other ages. Most studies addressing visual risk factors for MVCs by older dri...

journal_title：BMC ophthalmology

authors： Owsley C,McGwin G Jr,Antin JF,Wood JM,Elgin J

更新日期：2018-02-07 00:00:00

abstract：BACKGROUND:Cavernous carotid aneurysm (CCA) represents 2-9% of all intracranial aneurysms and 15% of internal carotid artery (ICA) aneurysms; additionally, giant aneurysms are those aneurysms that are > 25 mm in size. Bilateral CCAs account for 11-29% of patients and are commonly associated with structural weaknesses i...

journal_title：BMC ophthalmology

authors： Vanikieti K,Poonyathalang A,Jindahra P,Cheecharoen P,Chokthaweesak W

更新日期：2018-02-02 00:00:00

abstract：BACKGROUND:Retinopathy of Prematurity (ROP) is one of the most common causes of childhood blindness worldwide. Comparisons of anti-VEGF and laser treatments in ROP are relatively lacking, and the data are scattered and limited. The objective of this meta-analysis is to compare the efficacy of both treatments in type-1 ...

journal_title：BMC ophthalmology

authors： Li Z,Zhang Y,Liao Y,Zeng R,Zeng P,Lan Y

更新日期：2018-01-30 00:00:00

abstract：BACKGROUND:To assess the precision and agreement of measurements of higher order aberrations (HOAs) obtained with a ray tracing aberrometer (iTrace) and a Hartmann-Shack aberrometer (Topcon KR-1 W). METHODS:Prospective evaluation of the diagnostic test. Data from the right eyes of 92 normal subjects obtained using the...

journal_title：BMC ophthalmology

authors： Xu Z,Hua Y,Qiu W,Li G,Wu Q

更新日期：2018-01-27 00:00:00

abstract：BACKGROUND:Dry eye is a common problem that affects many people worldwide, reducing quality of life and impacting daily activities. A qualitative approach often used in medicine and other disciplines is used to evaluate how people with dry eye cope with this impact. METHODS:Six focus group sessions were conducted at t...

journal_title：BMC ophthalmology

authors： Yeo S,Tong L

更新日期：2018-01-16 00:00:00

abstract：BACKGROUND:Immunoglobulin G4-related disease (IgG4-rd) is characterized by lymphoplasmacytic infiltration and tissue fibrosis. Orbital manifestations of IgG4-rd may include unilateral or bilateral proptosis, cicatricial extraocular muscle myopathy, orbital inflammation and pain which may mimic ophthalmic Graves' diseas...

journal_title：BMC ophthalmology

authors： Erdei A,Steiber Z,Molnar C,Berenyi E,Nagy EV

更新日期：2018-01-12 00:00:00

abstract：BACKGROUND:The aim of this study was to evaluate the efficacy and safety of transepithelial corneal collagen crosslinking (transepithelial CXL) versus standard corneal collagen crosslinking (epithelium-off CXL) on keratoconus. METHODS:Eligible studies were identified by systematically searching PubMed, the Cochrane Li...

journal_title：BMC ophthalmology

authors： Li W,Wang B

更新日期：2017-12-28 00:00:00

abstract：BACKGROUND:Silicone oil tamponade is more frequently reserved for cases of complex retinal detachment. We describe the effects of different variations in oil ratios with the relatively unknown technique of double oil tamponade. METHODS:Retrospective case note review of nine patients with complex rhegmatogenous retinal...

journal_title：BMC ophthalmology

authors： MacGregor C,Jonas A,Hanifudin A,Lochhead J

更新日期：2017-12-28 00:00:00

abstract：BACKGROUND:To report a case of proliferative diabetic retinopathy (PDR) exhibiting the appearance of scintillating particles presumed to be crystallin inside the intravitreal cavity after laser photocoagulation. CASE PRESENTATION:A 56-year-old male patient presented at our outpatient clinic after becoming aware of dec...

journal_title：BMC ophthalmology

authors： Kohmoto R,Kobayashi T,Sato T,Kimura D,Fukumoto M,Tajiri K,Kida T,Ikeda T

更新日期：2017-12-19 00:00:00